Dual Targeting Factors Are Required for LXG Toxin Export by the Bacterial Type VIIb Secretion System

Dual Targeting Factors Are Required for LXG Toxin Export by the Bacterial Type VIIb Secretion System

ABSTRACT Bacterial type VIIb secretion systems (T7SSb) are multisubunit integral membrane protein complexes found in Firmicutes that play a role in both bacterial competition and virulence by secreting toxic effector proteins. The majority of characterized T7SSb effectors adopt a polymorphic domain...

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Bibliographic Details
Main Authors: Timothy A. Klein, Dirk W. Grebenc, Prakhar Y. Shah, Owen D. McArthur, Brandon H. Dickson, Michael G. Surette, Youngchang Kim, John C. Whitney
Format: Article
Language:English
Published: American Society for Microbiology 2022-10-01
Series:mBio
Subjects:
Type VII secretion system
protein secretion
protein-protein interactions
bacterial antagonism
antibacterial toxins
X-ray crystallography
Online Access:https://journals.asm.org/doi/10.1128/mbio.02137-22

Internet

https://journals.asm.org/doi/10.1128/mbio.02137-22

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