Amelioration of streptozotocin-induced diabetes in mice with cells derived from human marrow stromal cells.

Pluri-potent bone marrow stromal cells (MSCs) provide an attractive opportunity to generate unlimited glucose-responsive insulin-producing cells for the treatment of diabetes. We explored the potential for human MSCs (hMSCs) to be differentiated into glucose-responsive cells through a non-viral gene...

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Bibliographic Details
Main Authors: Min Zhao, Stephanie A Amiel, Sanaz Ajami, Jie Jiang, Mohamed Rela, Nigel Heaton, Guo Cai Huang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-07-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2441861?pdf=render