Ab locks for improving the selectivity and safety of antibody drugs
Abstract Monoclonal antibodies (mAbs) are a major targeted therapy for malignancies, infectious diseases, autoimmune diseases, transplant rejection and chronic inflammatory diseases due to their antigen specificity and longer half-life than conventional drugs. However, long-term systemic antigen neu...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2020-06-01
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Series: | Journal of Biomedical Science |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s12929-020-00652-z |