The relative contribution of DNA methylation and genetic variants on protein biomarkers for human diseases.

Associations between epigenetic alterations and disease status have been identified for many diseases. However, there is no strong evidence that epigenetic alterations are directly causal for disease pathogenesis. In this study, we combined SNP and DNA methylation data with measurements of protein b...

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Bibliographic Details
Main Authors: Muhammad Ahsan, Weronica E Ek, Mathias Rask-Andersen, Torgny Karlsson, Allan Lind-Thomsen, Stefan Enroth, Ulf Gyllensten, Åsa Johansson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-09-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC5617224?pdf=render