Coexpression network analysis of the adult brain sheds light on the pathogenic mechanism of DDR1 in schizophrenia and bipolar disorder

Abstract DDR1 has been linked to schizophrenia (SCZ) and bipolar disorder (BD) in association studies. DDR1 encodes 58 distinct transcripts, which can be translated into five isoforms (DDR1a-e) and are expressed in the brain. However, the transcripts expressed in each brain cell type, their function...

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Bibliographic Details
Main Authors: Selena Aranda, Gerard Muntané, Elisabet Vilella
Format: Article
Language:English
Published: Nature Publishing Group 2024-02-01
Series:Translational Psychiatry
Online Access:https://doi.org/10.1038/s41398-024-02823-0