Polymorphism of the endothelin-1 gene (rs5370) is a potential contributor to sickle cell disease pathophysiology

Sickle cell disease has been shown to demonstrate extensive variability in disease severity among and between individuals, the variability highlighted by differing genetic haplotypes. Despite the abundance of reports of functional significance due to polymorphisms of endothelial nitric oxide synthas...

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Autori principali: Kristen G. Navarro, Smith E. Agyingi, Chinedu K. Nwabuobi, Bolaji N. Thomas
Natura: Articolo
Lingua:English
Pubblicazione: KeAi Communications Co., Ltd. 2016-12-01
Serie:Genes and Diseases
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Accesso online:http://www.sciencedirect.com/science/article/pii/S2352304216300381