Polymorphism of the endothelin-1 gene (rs5370) is a potential contributor to sickle cell disease pathophysiology

Sickle cell disease has been shown to demonstrate extensive variability in disease severity among and between individuals, the variability highlighted by differing genetic haplotypes. Despite the abundance of reports of functional significance due to polymorphisms of endothelial nitric oxide synthas...

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Bibliographic Details
Main Authors: Kristen G. Navarro, Smith E. Agyingi, Chinedu K. Nwabuobi, Bolaji N. Thomas
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2016-12-01
Series:Genes and Diseases
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2352304216300381