Inhibitory Effect of Chlorogenic Acid Analogues Comprising Pyridine and Pyrimidine on α-MSH-Stimulated Melanogenesis and Stability of Acyl Analogues in Methanol

Inhibitory Effect of Chlorogenic Acid Analogues Comprising Pyridine and Pyrimidine on α-MSH-Stimulated Melanogenesis and Stability of Acyl Analogues in Methanol

In continuation of studies for α-MSH stimulated melanogenesis inhibitors, we have evaluated the design, synthesis, and activity of a new series of chlorogenic acid (CGA) analogues comprising pyridine, pyrimidine, and diacyl derivatives. Among nineteen synthesized compounds, most of them (fifteen) ex...

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Bibliographic Details
Main Authors: Jaeuk Sim, Srinu Lanka, Jeong-Woong Jo, Chhabi Lal Chaudhary, Manjunatha Vishwanath, Chan-Hyun Jung, Young-Hee Lee, Eun-Yeong Kim, Young-Soo Kim, Soon-Sil Hyun, Hee-Soon Lee, Kiho Lee, Seung-Yong Seo, Mayavan Viji, Jae-Kyung Jung
Format: Article
Language:English
Published: MDPI AG 2021-11-01
Series:Pharmaceuticals
Subjects:
chlorogenic acid
α-MSH-stimulated melanogenesis
pyridine
pyrimidine
B16 melanoma cells
Online Access:https://www.mdpi.com/1424-8247/14/11/1176

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https://www.mdpi.com/1424-8247/14/11/1176

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