A Novel Kindred with Familial Gastrointestinal Stromal Tumors Caused by a Rare <i>KIT</i> Germline Mutation (N655K): Clinico-Pathological Presentation and TKI Sensitivity

Gastrointestinal stromal tumors (GISTs), the most common mesenchymal tumors of the gastrointestinal tract, are characterized by activating mutations in <i>KIT</i> or <i>PDGFRA</i> genes. The vast majority of GISTs are sporadic, but rare hereditary forms have been reported, of...

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Bibliographic Details
Main Authors: Mara Fornasarig, Daniela Gasparotto, Luisa Foltran, Michele Campigotto, Sara Lombardi, Elisa Del Savio, Angela Buonadonna, Fabio Puglisi, Sandro Sulfaro, Vincenzo Canzonieri, Renato Cannizzaro, Roberta Maestro
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:Journal of Personalized Medicine
Subjects:
Online Access:https://www.mdpi.com/2075-4426/10/4/234