A Novel Kindred with Familial Gastrointestinal Stromal Tumors Caused by a Rare <i>KIT</i> Germline Mutation (N655K): Clinico-Pathological Presentation and TKI Sensitivity
Gastrointestinal stromal tumors (GISTs), the most common mesenchymal tumors of the gastrointestinal tract, are characterized by activating mutations in <i>KIT</i> or <i>PDGFRA</i> genes. The vast majority of GISTs are sporadic, but rare hereditary forms have been reported, of...
Main Authors: | , , , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2020-11-01
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Series: | Journal of Personalized Medicine |
Subjects: | |
Online Access: | https://www.mdpi.com/2075-4426/10/4/234 |