Prostaglandin E2 amplifies IL-17 production by γδ T cells during barrier inflammation

Prostaglandin E2 amplifies IL-17 production by γδ T cells during barrier inflammation

Summary: Interleukin-17 (IL-17)-producing γδ (γδ17) T cells are innate-like lymphocytes that contribute to protective anti-microbial responses but are also implicated in pathogenic inflammation at barrier sites. Understanding tissue-specific signals that regulate this subset is important to boost ho...

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Bibliographic Details
Main Authors: Barbara Polese, Bavanitha Thurairajah, Hualin Zhang, Cindy Leung Soo, Clara A. McMahon, Ghislaine Fontes, Sabah N.A. Hussain, Valerie Abadie, Irah L. King
Format: Article
Language:English
Published: Elsevier 2021-07-01
Series:Cell Reports
Subjects:
γδT cells
IL-17
skin
gut
inflammation
colitis
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124721008731

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http://www.sciencedirect.com/science/article/pii/S2211124721008731

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