CCAAT enhancer binding protein delta activates vesicle associated membrane protein 3 transcription to enhance chemoresistance and extracellular PD-L1 expression in triple-negative breast cancer

CCAAT enhancer binding protein delta activates vesicle associated membrane protein 3 transcription to enhance chemoresistance and extracellular PD-L1 expression in triple-negative breast cancer

Abstract Background Chemoresistance and immunosuppression are two major obstacles in the current anti-cancer treatments. This study investigates the involvements of a CCAAT enhancer binding protein delta (CEBPD)/vesicle associated membrane protein 3 (VAMP3) axis in paclitaxel (PTX) resistance and im...

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Bibliographic Details
Main Authors: Yan Zhao, Yangyang Yu, Xiangmin Li, Ayao Guo
Format: Article
Language:English
Published: BMC 2024-04-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
CEBPD
VAMP3
Triple-negative breast cancer
Autophagy
Paclitaxel resistance
Immune evasion
Online Access:https://doi.org/10.1186/s13046-024-03041-8

Internet

https://doi.org/10.1186/s13046-024-03041-8

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