PVP-H<sub>2</sub>O<sub>2</sub> Complex as a New Stressor for the Accelerated Oxidation Study of Pharmaceutical Solids

Reactive impurities, such as hydrogen peroxide in excipients, raise a great concern over the chemical stability of pharmaceutical products. Traditional screening methods of spiking impurities into solid drug-excipient mixtures oversimplify the micro-environment and the physical state of such impurit...

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Bibliographic Details
Main Authors: Dattatray Modhave, Brenda Barrios, Amrit Paudel
Format: Article
Language:English
Published: MDPI AG 2019-09-01
Series:Pharmaceutics
Subjects:
Online Access:https://www.mdpi.com/1999-4923/11/9/457