A Direct Method for Synthesis of Quinoxalines and Quinazolinones Using Epoxides as Alkyl Precursor

An iodine-mediated one-pot synthesis of pyrrolo/indolo [1,2-<i>a</i>]quinoxalines and quinazolin-4-one via utilizing epoxides as alkyl precursors under metal-free conditions has been described. Both 1-(2-aminophenyl)-pyrrole and 2-aminobenzamide could be applied to this protocol. A total...

Full description

Bibliographic Details
Main Authors: Xueyan Lv, Lili Lv, Shichen Li, Chengcheng Ding, Bingchuan Yang, Chen Ma
Format: Article
Language:English
Published: MDPI AG 2023-11-01
Series:Molecules
Subjects:
Online Access:https://www.mdpi.com/1420-3049/28/21/7391