Personalized Nutrition Using Microbial Metabolite Phenotype to Stratify Participants and Non-Invasive Host Exfoliomics Reveal the Effects of Flaxseed Lignan Supplementation in a Placebo-Controlled Crossover Trial

Personalized Nutrition Using Microbial Metabolite Phenotype to Stratify Participants and Non-Invasive Host Exfoliomics Reveal the Effects of Flaxseed Lignan Supplementation in a Placebo-Controlled Crossover Trial

High-fiber plant foods contain lignans that are converted to bioactive enterolignans, enterolactone (ENL) and enterodiol (END) by gut bacteria. Previously, we conducted an intervention study to gain mechanistic insight into the potential chemoprotective effects of flaxseed lignan supplementation (se...

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Bibliographic Details
Main Authors: Destiny A. Mullens, Ivan Ivanov, Meredith A. J. Hullar, Timothy W. Randolph, Johanna W. Lampe, Robert S. Chapkin
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:Nutrients
Subjects:
human intervention
colon
lignan
enterolactone
secoisolariciresinol
gene expression
Online Access:https://www.mdpi.com/2072-6643/14/12/2377

Internet

https://www.mdpi.com/2072-6643/14/12/2377

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