Early immune innate hallmarks and microbiome changes across the gut during Escherichia coli O157: H7 infection in cattle

Abstract The zoonotic enterohemorrhagic Escherichia coli (EHEC) O157: H7 bacterium causes diarrhea, hemorrhagic colitis, and hemolytic uremic syndrome (HUS) in humans. Cattle are primary reservoirs and EHEC O157: H7; the bacteria predominately inhabit the colon and recto-anal junctions (RAJ). The ea...

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Bibliographic Details
Main Authors: Mariano Larzábal, Wanderson Marques Da Silva, Anmol Multani, Lucas E. Vagnoni, Dadin P. Moore, Maia S. Marin, Nahuel A. Riviere, Fernando O. Delgado, Daniel A. Vilte, Matias Romero Victorica, Tao Ma, Luo Le Guan, Paola Talia, Angel Cataldi, Eduardo R. Cobo
Format: Article
Language:English
Published: Nature Portfolio 2020-12-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-020-78752-x