Microplastics caused embryonic growth retardation and placental dysfunction in pregnant mice by activating GRP78/IRE1α/JNK axis induced apoptosis and endoplasmic reticulum stress

Microplastics caused embryonic growth retardation and placental dysfunction in pregnant mice by activating GRP78/IRE1α/JNK axis induced apoptosis and endoplasmic reticulum stress

Abstract Microplastics (MPs), a brand-new class of worldwide environmental pollutant, have received a lot of attention. MPs are consumed by both humans and animals through water, food chain and other ways, which may cause potential health risks. However, the effects of MPs on embryonic development,...

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Bibliographic Details
Main Authors: Jun Bai, Yuzeng Wang, Siwei Deng, Ying Yang, Sheng Chen, Zhenlong Wu
Format: Article
Language:English
Published: BMC 2024-09-01
Series:Particle and Fibre Toxicology
Subjects:
Microplastics
Pregnant mice
Placenta
Developmental toxicity
Endoplasmic reticulum stress
MAPK pathway
Online Access:https://doi.org/10.1186/s12989-024-00595-5

Internet

https://doi.org/10.1186/s12989-024-00595-5

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