Inhibition of EZH2 primes the cardiac gene activation via removal of epigenetic repression during human direct cardiac reprogramming

Cardiovascular disease, until now, is still the leading cause of death in the United States. Due to the limited regenerative capacity of adult hearts, the damage caused by heart injury cannot be reversed and eventually progress into heart failure. In need of cardiovascular disease treatment, many th...

Full description

Bibliographic Details
Main Authors: Yawen Tang, Lianzhong Zhao, Xufen Yu, Jianyi Zhang, Li Qian, Jian Jin, Rui Lu, Yang Zhou
Format: Article
Language:English
Published: Elsevier 2021-05-01
Series:Stem Cell Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1873506121002117