CRX-527 as a candidate adjuvant in a recombinant BCG-based malaria vaccine

Objective: To investigate the role of CRX-527, a Toll-like receptor 4 agonist, as the possible adjuvant for recombinant Mycobacterium bovis Bacillus Calmette-Guerin expressing merozoite surface protein 1C (BCG-MSP-1C). Methods: The mice were immunized with BCG and BCG-MSP-1C in the presence and abse...

Full description

Bibliographic Details
Main Authors: Nor Munirah Zakaria, Muhammad Adamu Abbas, Rapeah Suppian
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2024-01-01
Series:Asian Pacific Journal of Tropical Biomedicine
Subjects:
Online Access:http://www.apjtb.org/article.asp?issn=2221-1691;year=2024;volume=14;issue=1;spage=1;epage=7;aulast=Zakaria