Immunostimulatory activity and structure-activity relationship of epimedin B from Epimedium brevicornu Maxim.

Immunostimulatory activity and structure-activity relationship of epimedin B from Epimedium brevicornu Maxim.

Epimedii Folium (EF, Epimedium brevicornu Maxim.), a traditional botanical drug, is famous for treating bone fractures, joint diseases, and several chronic illnesses. However, some studies indicated that EF could induce idiosyncratic drug-induced liver injury (IDILI) in the clinic. The NLRP3 inflamm...

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Bibliographic Details
Main Authors: Yuan Gao, Wei Shi, Can Tu, Peng Li, Guanyu Zhao, Xiaohe Xiao, Jiabo Wang, Zhaofang Bai
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-10-01
Series:Frontiers in Pharmacology
Subjects:
epimedin B
idiosyncratic drug-induced liver injury
NLRP3 inflammasome
epimedii folium
mitochondrial ROS
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2022.1015846/full

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https://www.frontiersin.org/articles/10.3389/fphar.2022.1015846/full

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