Serine/Threonine Protein Phosphatase-Mediated Control of the Peptidoglycan Cross-Linking <sc>l</sc>,<sc>d</sc><sc>-</sc>Transpeptidase Pathway in <named-content content-type="genus-species">Enterococcus faecium</named-content>
ABSTRACT The last step of peptidoglycan polymerization involves two families of unrelated transpeptidases that are the essential targets of β-lactam antibiotics. d,d-transpeptidases of the penicillin-binding protein (PBP) family are active-site serine enzymes that use pentapeptide precursors and are...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
American Society for Microbiology
2014-08-01
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| Series: | mBio |
| Online Access: | https://journals.asm.org/doi/10.1128/mBio.01446-14 |