Is the endogenous ligand for PEAR1 a proteoglycan: clues from the sea

Platelet Endothelial Aggregation Receptor 1 (PEAR1) is an orphan receptor of unknown function which mediates powerful activation of platelets and endothelial cells in response to crosslinking by antibodies and sulfated polysaccharides belonging to the dextran and fucoidan families. PEAR1 is a single...

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Bibliographic Details
Main Authors: Caroline Kardeby, Foteini-Nafsika Damaskinaki, Yi Sun, Stephen P. Watson
Format: Article
Language:English
Published: Taylor & Francis Group 2021-08-01
Series:Platelets
Online Access:http://dx.doi.org/10.1080/09537104.2020.1863938