Efficacy and safety of the endothelin-1 receptor antagonist macitentan in epicardial and microvascular vasospasm; a proof-of-concept study

Efficacy and safety of the endothelin-1 receptor antagonist macitentan in epicardial and microvascular vasospasm; a proof-of-concept study

Background: Treatment of patients diagnosed with angina due to epicardial or microvascular coronary artery spasm (CAS) is challenging because patients often remain symptomatic despite conventional pharmacological therapy. In this prospective, randomized, double-blind, placebo-controlled, sequential...

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Bibliographic Details
Main Authors: Rutger G.T. Feenstra, Tijn P.J. Jansen, S. Matthijs Boekholdt, Janet E. Brouwer, Margriet I. Klees, Yolande Appelman, Marianne E. Wittekoek, Tim P. van de Hoef, Robbert J. de Winter, Jan J. Piek, Peter Damman, Marcel A.M. Beijk
Format: Article
Language:English
Published: Elsevier 2023-08-01
Series:International Journal of Cardiology: Heart & Vasculature
Subjects:
Vasospastic angina
Microvascular angina
Coronary artery spasm
Macitentan
Proof of concept
Online Access:http://www.sciencedirect.com/science/article/pii/S2352906723000696

Internet

http://www.sciencedirect.com/science/article/pii/S2352906723000696

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