Mechanism of Anticonvulsant Action of ACTH

The hypothesis that systemic or intraventricular administration of corticotropin (ACTH) acts directly on limbic neurons to modulate corticotropin-releasing hormone (CRH) gene expression, independently of adrenal stimulation, was tested and confirmed in experiments on developing rats (9-11 days postn...

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Bibliographic Details
Main Author: J Gordon Millichap
Format: Article
Language:English
Published: Pediatric Neurology Briefs Publishers 2001-03-01
Series:Pediatric Neurology Briefs
Subjects:
Online Access:https://www.pediatricneurologybriefs.com/articles/1816