Transcriptional and Post-Transcriptional Regulation of Thrombospondin-1 Expression: A Computational Model.

Hypoxia is an important physiological stress signal that drives angiogenesis, the formation of new blood vessels. Besides an increase in the production of pro-angiogenic signals such as vascular endothelial growth factor (VEGF), hypoxia also stimulates the production of anti-angiogenic signals. Thro...

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Bibliographic Details
Main Authors: Chen Zhao, Jeffrey S Isenberg, Aleksander S Popel
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC5207393?pdf=render