Alzheimer’s Disease and Tau Self-Assembly: In the Search of the Missing Link

Alzheimer’s Disease and Tau Self-Assembly: In the Search of the Missing Link

Alzheimer’s disease (AD) is a multifactorial neurodegenerative disease characterized by progressive cognitive impairment, apathy, and neuropsychiatric disorders. Two main pathological hallmarks have been described: neurofibrillary tangles, consisting of tau oligomers (hyperphosphorylated tau) and Aβ...

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Bibliographic Details
Main Authors: Andrea González, Sandeep Kumar Singh, Macarena Churruca, Ricardo B. Maccioni
Format: Article
Language:English
Published: MDPI AG 2022-04-01
Series:International Journal of Molecular Sciences
Subjects:
Alzheimer’s disease
tau protein
polyanions
polyphosphates
neurofibrillary tangles
Online Access:https://www.mdpi.com/1422-0067/23/8/4192

Internet

https://www.mdpi.com/1422-0067/23/8/4192

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