Case Report: Late Onset of Myelodysplastic Syndrome From Donor Progenitor Cells After Allogeneic Stem Cell Transplantation. Which Lessons Can We Draw From the Reported Case?

Case Report: Late Onset of Myelodysplastic Syndrome From Donor Progenitor Cells After Allogeneic Stem Cell Transplantation. Which Lessons Can We Draw From the Reported Case?

BackgroundMyelodysplastic syndromes and acute leukemias after allogeneic stem cell transplantation (allo-SCT) are mainly caused by recurrence of the primitive leukemic clones. More rarely, they originate from donor hematopoietic stem cells, developing the so-called donor cell leukemia (DCL) or myelo...

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Bibliographic Details
Main Authors: Mirko Farina, Simona Bernardi, Lisa Gandolfi, Camilla Zanaglio, Enrico Morello, Alessandro Turra, Tatiana Zollner, Doriana Gramegna, Benedetta Rambaldi, Federica Cattina, Nicola Polverelli, Michele Malagola, Domenico Russo
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-10-01
Series:Frontiers in Oncology
Subjects:
donor cell myelodysplasia
transplant
leukemogenesis
immunosurveillance
immunosuppression
stem cells
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2020.564521/full

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https://www.frontiersin.org/article/10.3389/fonc.2020.564521/full

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