Enhancing nasopharyngeal carcinoma cell radiosensitivity by suppressing AKT/mTOR via CENP-N knockdown

Enhancing nasopharyngeal carcinoma cell radiosensitivity by suppressing AKT/mTOR via CENP-N knockdown

Abstract Objective Investigating the impact of centromere protein N (CENP-N) on radiosensitivity of nasopharyngeal carcinoma (NPC) cells. Methods Using immunohistochemistry and immunofluorescence to detect CENP-N expression in tissues from 35 patients with radiosensitive or radioresistant NPC. Asses...

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Bibliographic Details
Main Authors: Li-Zhi Wu, You Zou, Bin-Ru Wang, Hai-Feng Ni, Yong-Gang Kong, Qing-Quan Hua, Shi-Ming Chen
Format: Article
Language:English
Published: BMC 2023-11-01
Series:Journal of Translational Medicine
Subjects:
Nasopharyngeal carcinoma
CENP-N
Radiosensitivity
Apoptosis
Cell cycle
AKT/mTOR signaling pathway
Online Access:https://doi.org/10.1186/s12967-023-04654-x

Internet

https://doi.org/10.1186/s12967-023-04654-x

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