Partial Genetic Deletion of Klotho Aggravates Cardiac Calcium Mishandling in Acute Kidney Injury

Partial Genetic Deletion of Klotho Aggravates Cardiac Calcium Mishandling in Acute Kidney Injury

Acute kidney injury (AKI) is associated with an elevated risk of cardiovascular major events and mortality. The pathophysiological mechanisms underlying the complex cardiorenal network interaction remain unresolved. It is known that the presence of AKI and its evolution are significantly associated...

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Bibliographic Details
Main Authors: Laura González-Lafuente, José Alberto Navarro-García, Ángela Valero-Almazán, Elena Rodríguez-Sánchez, Sara Vázquez-Sánchez, Elisa Mercado-García, Patricia Pineros, Jonay Poveda, María Fernández-Velasco, Makoto Kuro-O, Luis M. Ruilope, Gema Ruiz-Hurtado
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:International Journal of Molecular Sciences
Subjects:
klotho
acute kidney injury
cardiorenal syndrome
cardiomyocyte
calcium handling
arrhythmia
Online Access:https://www.mdpi.com/1422-0067/24/2/1322

Internet

https://www.mdpi.com/1422-0067/24/2/1322

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