CAR-modified Cellular Therapies in Chronic Lymphocytic Leukemia: Is the Uphill Road Getting Less Steep?
The clinical development of chimeric antigen receptor (CAR) T-cell therapy has been more challenging for chronic lymphocytic leukemia (CLL) compared to other settings. One of the main reasons is the CLL-associated state of immune dysfunction that specifically involves patient-derived T cells. Here,...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Wiley
2023-12-01
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Series: | HemaSphere |
Online Access: | http://journals.lww.com/10.1097/HS9.0000000000000988 |