Enhancing Hepatic Fatty Acid Oxidation as a Strategy for Reversing Metabolic Disorders Programmed by Maternal Undernutrition During Gestation

Enhancing Hepatic Fatty Acid Oxidation as a Strategy for Reversing Metabolic Disorders Programmed by Maternal Undernutrition During Gestation

Background/Aims: Moderate maternal calorie-restriction during gestation programmes offspring for a major propensity to develop metabolic alterations in adulthood. We aimed to assess whether increased hepatic fatty-acid oxidation (FAO), at early ages, by gene transfer of Cpt1am (active mutant of carn...

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Bibliographic Details
Main Authors: Juana María Torrens, Josep M. Orellana-Gavaldà, Mariona Palou, Juana Sánchez, Laura Herrero, Catalina Picó, Dolors Serra, Andreu Palou
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2014-05-01
Series:Cellular Physiology and Biochemistry
Subjects:
Cpt1a
Calorie restriction
Gestation
Gene transference
Liver
Online Access:http://www.karger.com/Article/FullText/358714

Internet

http://www.karger.com/Article/FullText/358714

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