Verteporfin ameliorates fibrotic aspects of Dupuytren’s disease nodular fibroblasts irrespective the activation state of the cells

Abstract Dupuytren’s disease is a chronic, progressive fibroproliferative condition of the hand fascia which results in digital contraction. So far, treatments do not directly interfere with the (myo)fibroblasts that are responsible for the formation of the collagen-rich cords and its contraction. H...

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Bibliographic Details
Main Authors: Nataly Puerta Cavanzo, Sophie A. Riesmeijer, Iris L. Holt-Kedde, Paul M. N. Werker, Bram Piersma, Peter Olinga, Ruud A. Bank
Format: Article
Language:English
Published: Nature Portfolio 2022-08-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-18116-9