Peptides Interfering 3A Protein Dimerization Decrease FMDV Multiplication.

Nonstructural protein 3A is involved in relevant functions in foot-and-mouth disease virus (FMDV) replication. FMDV 3A can form homodimers and preservation of the two hydrophobic α-helices (α1 and α2) that stabilize the dimer interface is essential for virus replication. In this work, small peptides...

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Bibliographic Details
Main Authors: Mónica González-Magaldi, Ángela Vázquez-Calvo, Beatriz G de la Torre, Javier Valle, David Andreu, Francisco Sobrino
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4624780?pdf=render