CD4-blockade can induce protection from peanut-induced anaphylaxis

CD4-blockade can induce protection from peanut-induced anaphylaxis

Monoclonal antibodies (mAb) have been shown effective in inducing immune tolerance in a range of animal models of autoimmunity, allergy, and transplantation. We investigated whether CD4-blockade, effective in inducing transplantation tolerance, could prevent systemic immune responses leading to anap...

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Bibliographic Details
Main Authors: Joana eDuarte, Marta eCaridade, Luis eGraca
Format: Article
Language:English
Published: Frontiers Media S.A. 2011-10-01
Series:Frontiers in Immunology
Subjects:
Anaphylaxis
Immune Tolerance
Regulatory T Cell
Anti-CD4 monoclonal antibody
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2011.00056/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fimmu.2011.00056/full

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