Functional EL-HN Fragment as a Potent Candidate Vaccine for the Prevention of Botulinum Neurotoxin Serotype E

Functional EL-HN Fragment as a Potent Candidate Vaccine for the Prevention of Botulinum Neurotoxin Serotype E

<i>Clostridium botulinum</i> produces botulinum neurotoxin (BoNT), which is the most toxic known protein and the causative agent of human botulism. BoNTs have similar structures and functions, comprising three functional domains: catalytic domain (L), translocation domain (HN), and recep...

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Bibliographic Details
Main Authors: Zhen Li, Jiansheng Lu, Xiao Tan, Rong Wang, Qing Xu, Yunzhou Yu, Zhixin Yang
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:Toxins
Subjects:
botulinum neurotoxin
functional fragment
L-HN fragment
subunit vaccine
immunoprotective effect
Online Access:https://www.mdpi.com/2072-6651/14/2/135

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https://www.mdpi.com/2072-6651/14/2/135

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