Treating intrauterine adhesion using conditionally reprogrammed physiological endometrial epithelial cells

Treating intrauterine adhesion using conditionally reprogrammed physiological endometrial epithelial cells

Abstract Background There is unmet need for effective therapies of intrauterine adhesions (IUAs) that are common cause of menstrual disturbance and infertility, since current clinical procedures do not improve prognosis for patients with moderate to severe IUA, with a recurrence rate of 23–50%. Stem...

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Bibliographic Details
Main Authors: Siyu Xia, Ming Wu, Xinhao Zhou, Xiu Zhang, Lina Ye, Kang Zhang, Yiyi Kang, Jun Liu, Yunci Zhang, Wang Wu, Dirong Dong, Hong Chen, Hui Li
Format: Article
Language:English
Published: BMC 2022-05-01
Series:Stem Cell Research & Therapy
Subjects:
Mouse endometrial epithelial cells (MEECs)
Conditional reprogramming (CR)
Intrauterine adhesion (IUA)
Regeneration and repair
Estrogen/progesterone receptor (ERα/ PR)
Online Access:https://doi.org/10.1186/s13287-022-02860-w

Internet

https://doi.org/10.1186/s13287-022-02860-w

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