Multiple kinases inhibit origin licensing and helicase activation to ensure reductive cell division during meiosis

Meiotic cells undergo a single round of DNA replication followed by two rounds of chromosome segregation (the meiotic divisions) to produce haploid gametes. Both DNA replication and chromosome segregation are similarly regulated by CDK oscillations in mitotic cells. Yet how these two events are unco...

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Bibliographic Details
Main Authors: David V Phizicky, Luke E Berchowitz, Stephen P Bell
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2018-02-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/33309