Steady-state distributions of nascent RNA for general initiation mechanisms

Fluctuations in the number of nascent RNA accurately reflect transcriptional activity. However, mathematical models predicting their distributions are difficult to solve analytically due to their non-Markovian nature stemming from transcriptional elongation. Here we circumvent this problem by derivi...

Full description

Bibliographic Details
Main Authors: Juraj Szavits-Nossan, Ramon Grima
Format: Article
Language:English
Published: American Physical Society 2023-01-01
Series:Physical Review Research
Online Access:http://doi.org/10.1103/PhysRevResearch.5.013064