Independent Membrane Binding Properties of the Caspase Generated Fragments of the Beaded Filament Structural Protein 1 (BFSP1) Involves an Amphipathic Helix

Independent Membrane Binding Properties of the Caspase Generated Fragments of the Beaded Filament Structural Protein 1 (BFSP1) Involves an Amphipathic Helix

Background: BFSP1 (beaded filament structural protein 1) is a plasma membrane, Aquaporin 0 (AQP0/MIP)-associated intermediate filament protein expressed in the eye lens. BFSP1 is myristoylated, a post-translation modification that requires caspase cleavage at D433. Bioinformatic analyses suggested t...

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Bibliographic Details
Main Authors: Miguel Jarrin, Alexia A. Kalligeraki, Alice Uwineza, Chris S. Cawood, Adrian P. Brown, Edward N. Ward, Khoa Le, Stefanie Freitag-Pohl, Ehmke Pohl, Bence Kiss, Antal Tapodi, Roy A. Quinlan
Format: Article
Language:English
Published: MDPI AG 2023-06-01
Series:Cells
Subjects:
lens
cataract
intermediate filaments
amphipathic helix
oligomerisation
intrinsically disordered domain
Online Access:https://www.mdpi.com/2073-4409/12/12/1580

Internet

https://www.mdpi.com/2073-4409/12/12/1580

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