Pleiotropic influence of DNA methylation QTLs on physiological and ageing traits
DNA methylation is influenced by genetic and non-genetic factors. Here, we chart quantitative trait loci (QTLs) that modulate levels of methylation at highly conserved CpGs using liver methylome data from mouse strains belonging to the BXD family. A regulatory hotspot on chromosome 5 had the highest...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
Taylor & Francis Group
2023-12-01
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Series: | Epigenetics |
Subjects: | |
Online Access: | http://dx.doi.org/10.1080/15592294.2023.2252631 |