Integracides: Tetracyclic Triterpenoids from <i>Fusarium</i> sp.—Their 5-Lipoxygenase Inhibitory Potential and Structure–Activity Relation Using In Vitro and Molecular Docking Studies

Integracides: Tetracyclic Triterpenoids from <i>Fusarium</i> sp.—Their 5-Lipoxygenase Inhibitory Potential and Structure–Activity Relation Using In Vitro and Molecular Docking Studies

Inflammation is a complicated disorder that is produced as a result of consecutive processes. 5-LOX (5-lipoxygenase) is accountable for various inflammation mediators and leukotrienes synthesis, and its inhibition is the target of anti-inflammation therapeutics. Fungi have acquired enormous attentiv...

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Bibliographic Details
Main Authors: Maan T. Khayat, Khadijah A. Mohammad, Gamal A. Mohamed, Martin K. Safo, Sabrin R. M. Ibrahim
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Life
Subjects:
<i>Fusarium</i> sp.
integracides
triterpenoids
5-lipoxygenase
inflammation
drug discovery
Online Access:https://www.mdpi.com/2075-1729/12/12/2095

Internet

https://www.mdpi.com/2075-1729/12/12/2095

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