The pivotal role of micro-environmental cells in a human blood–brain barrier in vitro model of cerebral ischemia: functional and transcriptomic analysis

Abstract Background The blood–brain barrier (BBB) is altered in several diseases of the central nervous system. For example, the breakdown of the BBB during cerebral ischemia in stroke or traumatic brain injury is a hallmark of the diseases’ progression. This functional damage is one key event which...

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Bibliographic Details
Main Authors: Anna Gerhartl, Nadja Pracser, Alexandra Vladetic, Sabrina Hendrikx, Heinz-Peter Friedl, Winfried Neuhaus
Format: Article
Language:English
Published: BMC 2020-03-01
Series:Fluids and Barriers of the CNS
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12987-020-00179-3