Assessment of denosumab treatment effects and imaging response in patients with giant cell tumor of bone

Assessment of denosumab treatment effects and imaging response in patients with giant cell tumor of bone

Abstract Background Denosumab has been shown to reduce tumor size and progression, reform mineralized bone, and increase intralesional bone density in patients with giant cell tumor of bone (GCTB); however, radiologic assessment of tumors in bone is challenging. The study objective was to assess tum...

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Bibliographic Details
Main Authors: Jacob Engellau, Leanne Seeger, Robert Grimer, Robert Henshaw, Hans Gelderblom, Edwin Choy, Sant Chawla, Peter Reichardt, Michael O’Neal, Amy Feng, Ira Jacobs, Zachary J. Roberts, Ada Braun, Bruce A. Bach
Format: Article
Language:English
Published: BMC 2018-09-01
Series:World Journal of Surgical Oncology
Subjects:
Giant cell tumor of bone
Denosumab
RANKL
Objective tumor response
Online Access:http://link.springer.com/article/10.1186/s12957-018-1478-3

Internet

http://link.springer.com/article/10.1186/s12957-018-1478-3

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