Dissecting in Vitro the Activation of Human Immune Response Induced by Shigella sonnei GMMA

Dissecting in Vitro the Activation of Human Immune Response Induced by Shigella sonnei GMMA

Generalized Modules for Membrane Antigens (GMMA) are outer membrane exosomes purified from Gram-negative bacteria genetically mutated to increase blebbing and reduce risk of reactogenicity. This is commonly achieved through modification of the lipid A portion of lipopolysaccharide. GMMA faithfully r...

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Bibliographic Details
Main Authors: Serena Tondi, Bruna Clemente, Carmen Esposito, Chiara Sammicheli, Simona Tavarini, Laura B. Martin, Omar Rossi, Francesca Micoli, Erika Bartolini, Michela Brazzoli, Cristina Ulivieri, Christoph J. Blohmke, Francesca Schiavetti
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-02-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
GMMA
Shigella sonnei
vaccines
immune response
hPBMCs
in vitro
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2022.767153/full

Internet

https://www.frontiersin.org/articles/10.3389/fcimb.2022.767153/full

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