Comprehensive analysis of the role of ICOS ( CD278 ) in pan-cancer prognosis and immunotherapy

Comprehensive analysis of the role of ICOS ( CD278 ) in pan-cancer prognosis and immunotherapy

Abstract Background The immunological checkpoint known as Inducible T Cell Costimulatory Factor (ICOS, Cluster of Differentiation, CD278) is activated and expressed on T cells. Both somatic cells and antigen-presenting cells expressed its ligand, ICOSL (including tumor cells in the tumor microenviro...

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Bibliographic Details
Main Authors: Xiashuang Zhao, Yongfeng Wang, Xianglai Jiang, Bangqian Mo, Chenyu Wang, Mingzheng Tang, Yao Rong, Guiqian Zhang, Ming Hu, Hui Cai
Format: Article
Language:English
Published: BMC 2023-02-01
Series:BMC Cancer
Subjects:
ICOS
Tumor immune
Immune checkpoint
Prognosis
Pan-cancer
Online Access:https://doi.org/10.1186/s12885-023-10564-4

Internet

https://doi.org/10.1186/s12885-023-10564-4

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