Gut Mucosal Microbiome Is Perturbed in Rheumatoid Arthritis Mice and Partly Restored after TDAG8 Deficiency or Suppression by Salicylanilide Derivative

Gut Mucosal Microbiome Is Perturbed in Rheumatoid Arthritis Mice and Partly Restored after TDAG8 Deficiency or Suppression by Salicylanilide Derivative

Rheumatoid arthritis (RA), an autoimmune disease, is characterized by chronic joint inflammation and pain. We previously found that the deletion of T-cell death-associated gene 8 (TDAG8) significantly reduces disease severity and pain in RA mice. Whether it is by modulating gut microbiota remains un...

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Bibliographic Details
Main Authors: Ngoc Tuan Nguyen, Wei-Hsin Sun, Tzu-Hsuan Chen, Po-Chun Tsai, Chih-Chen Chen, Shir-Ly Huang
Format: Article
Language:English
Published: MDPI AG 2022-03-01
Series:International Journal of Molecular Sciences
Subjects:
rheumatoid arthritis
pain
T-cell death-associated gene 8
microbiome
microbial diversity
Online Access:https://www.mdpi.com/1422-0067/23/7/3527

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https://www.mdpi.com/1422-0067/23/7/3527

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