A neglected neurodegenerative disease: Adult-onset globoid cell leukodystrophy

A neglected neurodegenerative disease: Adult-onset globoid cell leukodystrophy

Globoid cell leukodystrophy (GLD), or Krabbe disease (KD) is a rare neurodegenerative disease, and adult-onset GLD is more even neglected by clinicians. This review provides detailed discussions of the serum enzymes, genes, clinical manifestations, neuroimaging features, and therapies of GLD, with p...

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Bibliographic Details
Main Authors: Guode Wu, Zhenhua Li, Jing Li, Xin Li, Manxia Wang, Jing Zhang, Guangyao Liu, Pengfei Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Neuroscience
Subjects:
globoid cell leukodystrophy
Krabbe disease
adult-onset GLD
galactosylceramidase
GALC
psychosine
Online Access:https://www.frontiersin.org/articles/10.3389/fnins.2022.998275/full

Internet

https://www.frontiersin.org/articles/10.3389/fnins.2022.998275/full

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