Automated task training and longitudinal monitoring of mouse mesoscale cortical circuits using home cages

Automated task training and longitudinal monitoring of mouse mesoscale cortical circuits using home cages

We report improved automated open-source methodology for head-fixed mesoscale cortical imaging and/or behavioral training of home cage mice using Raspberry Pi-based hardware. Staged partial and probabilistic restraint allows mice to adjust to self-initiated headfixation over 3 weeks’ time with ~50%...

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Bibliographic Details
Main Authors: Timothy H Murphy, Nicholas J Michelson, Jamie D Boyd, Tony Fong, Luis A Bolanos, David Bierbrauer, Teri Siu, Matilde Balbi, Federico Bolanos, Matthieu Vanni, Jeff M LeDue
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2020-05-01
Series:eLife
Subjects:
cortex
homecage
automation
mesoscale
imaging
Online Access:https://elifesciences.org/articles/55964

Internet

https://elifesciences.org/articles/55964

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