An Efficient Peptidomics Screening for Exogenous Substrates and Inhibitory Peptides of the Dipeptidase ACE from Milk Hydrolysate

The dipeptidase angiotensin-I-converting enzyme (ACE) pre-incubation, liquid chromatography- mass spectrometry (LC-MS), and stable-isotope labeling were integrated for an efficient screening of ACE’s exogenous substrates from milk hydrolysate. Using this approach, 31 substrates were readily identifi...

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Bibliographic Details
Main Authors: Ju-Hsuan Huang, Nhung Thi Phuong Nong, Jue-Liang Hsu
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:Pharmaceutics
Subjects:
Online Access:https://www.mdpi.com/1999-4923/15/2/425