Immunoreactivities Against Different Tyrosine-Phosphatase 2 (IA-2)(256-760) Protein Domains Characterize Distinct Phenotypes in Subjects With LADA

Immunoreactivities Against Different Tyrosine-Phosphatase 2 (IA-2)(256-760) Protein Domains Characterize Distinct Phenotypes in Subjects With LADA

Antibodies (Abs) against intracellular epitopes of the tyrosine-phosphatase 2 (IA-2) are detected in type 1 diabetes. Abs directed against the IA-2(256-760) portion, with both intra- and extracellular epitopes, are present in people with latent autoimmune diabetes in adults (LADA) and in obese subje...

Full description

Bibliographic Details
Main Authors: Claudio Tiberti, Luca D’Onofrio, Francesca Panimolle, Simona Zampetti, Ernesto Maddaloni, Raffaella Buzzetti
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Endocrinology
Subjects:
diabetes
autoantibodies
IA-2 antibodies
tyrosine-phosphatase 2
obesity
LADA
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2022.921886/full

Internet

https://www.frontiersin.org/articles/10.3389/fendo.2022.921886/full

Similar Items