PRR11 promotes ccRCC tumorigenesis by regulating E2F1 stability

Proline rich 11 (PRR11), a novel tumor-related gene, has been identified in different tumors. However, the relevant biological functions of PRR11 in human clear cell renal cell carcinoma (ccRCC) have not been studied. In this study, we first identified PRR11 as a biomarker of ccRCC and predictor of...

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Bibliographic Details
Main Authors: Siming Chen, Zhiwen He, Tianchen Peng, Fenfang Zhou, Gang Wang, Kaiyu Qian, Lingao Ju, Yu Xiao, Xinghuan Wang
Format: Article
Language:English
Published: American Society for Clinical investigation 2021-10-01
Series:JCI Insight
Subjects:
Online Access:https://doi.org/10.1172/jci.insight.145172