Regulator of G protein signaling 16 restrains apoptosis in colorectal cancer through disrupting TRAF6-TAB2-TAK1-JNK/p38 MAPK signaling

Regulator of G protein signaling 16 restrains apoptosis in colorectal cancer through disrupting TRAF6-TAB2-TAK1-JNK/p38 MAPK signaling

Abstract Colorectal cancer (CRC) remains a major global cause of cancer-related mortality, lacking effective biomarkers and therapeutic targets. Revealing the critical pathogenic factors of CRC and the underlying mechanisms would offer potential therapeutic strategies for clinical application. G pro...

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Bibliographic Details
Main Authors: Hao Shen, Jie Yuan, Dafeng Tong, Bingchen Chen, Enda Yu, Guanglei Chen, Cheng Peng, Wenjun Chang, Jifu E, Fuao Cao
Format: Article
Language:English
Published: Nature Publishing Group 2024-06-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-024-06803-6

Internet

https://doi.org/10.1038/s41419-024-06803-6

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